Online Student Book


Thresholds and Toxicology

Thresholds and Toxicology Book Cover

Thresholds and Toxicology is a SEPUP module designed for use in grades 7–12. The module contains a series of 10 activities that provide approximately 3 weeks of instruction

Obtaining governmental approval for new drugs and medicines is not an easy task. Years of research, testing, and data collection are needed to make sure the product is safe for society as a whole. Students examine the historical development of the regulation process, and consider a modern day example using "lily juice," a hypothetical herbal remedy promoted to increase intelligence. They learn about thresholds, concentration, toxicity, and qualitative and quantitative data. Simulated toxicity tests on rats provide data that can be analyzed to decide whether the product should be distributed. Students are assessed on their ability to analyze data.


Each module includes a Teacher’s Guide containing reproducible student pages and a kit containing the equipment required to conduct the activities with five classes of 32 students. The Teacher’s Guide provides specific strategies to facilitate and assess student learning